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Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities

Polyomavirus infections occur commonly in humans and are normally nonfatal. However, in immunocompromised individuals, they are intractable and frequently fatal. Due to a lack of approved drugs to treat polyomavirus infections, cidofovir, a phosphonate nucleotide analog approved to treat cytomegalov...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Onwubiko, Nichodemus O., Diaz, Suraya A., Krečmerová, Marcela, Nasheuer, Heinz Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092500/
https://ncbi.nlm.nih.gov/pubmed/33288638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01641-20
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