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Reduced Candida glabrata Susceptibility Secondary to an FKS1 Mutation Developed during Candidemia Treatment

We describe a case of recurring Candida glabrata infection in a 68-year-old African-American female on caspofungin therapy. The initial isolate was susceptible, but isolates recovered during following relapses were not. All isolates were clonal, and high-MIC strains contained a mutation in the highl...

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Detalhes bibliográficos
Main Authors: Cleary, John D., Garcia-Effron, Guillermo, Chapman, Stanley W., Perlin, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415792/
https://ncbi.nlm.nih.gov/pubmed/18378714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01568-07
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