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Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus

The ability of daptomycin to produce bactericidal activity against Staphylococcus aureus while causing negligible cell lysis has been demonstrated using electron microscopy and the membrane integrity probes calcein and ToPro3. The formation of aberrant septa on the cell wall, suggestive of impairmen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cotroneo, Nicole, Harris, Robert, Perlmutter, Nancy, Beveridge, Terry, Silverman, Jared A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415783/
https://ncbi.nlm.nih.gov/pubmed/18378708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01410-07
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