In Vitro Bactericidal Activities of Daptomycin against Staphylococcus aureus and Enterococcus faecalis Are Not Mediated by Inhibition of Lipoteichoic Acid Biosynthesis

Previous studies have suggested that lipoteichoic acid biosynthesis inhibition is the mechanism of action of daptomycin. In this investigation, daptomycin inhibited all macromolecular synthesis in Staphylococcus aureus, Enterococcus faecalis, and Enterococcus hirae without kinetic or dose specificit...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Laganas, Valerie, Alder, Jeffrey, Silverman, Jared A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2682-2684.2003
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