In Vitro Bactericidal Activities of Daptomycin against Staphylococcus aureus and Enterococcus faecalis Are Not Mediated by Inhibition of Lipoteichoic Acid Biosynthesis

Previous studies have suggested that lipoteichoic acid biosynthesis inhibition is the mechanism of action of daptomycin. In this investigation, daptomycin inhibited all macromolecular synthesis in Staphylococcus aureus, Enterococcus faecalis, and Enterococcus hirae without kinetic or dose specificit...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Laganas, Valerie, Alder, Jeffrey, Silverman, Jared A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2682-2684.2003
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