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In Vitro Bactericidal Activities of Daptomycin against Staphylococcus aureus and Enterococcus faecalis Are Not Mediated by Inhibition of Lipoteichoic Acid Biosynthesis

Previous studies have suggested that lipoteichoic acid biosynthesis inhibition is the mechanism of action of daptomycin. In this investigation, daptomycin inhibited all macromolecular synthesis in Staphylococcus aureus, Enterococcus faecalis, and Enterococcus hirae without kinetic or dose specificit...

詳細記述

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書誌詳細
主要な著者: Laganas, Valerie, Alder, Jeffrey, Silverman, Jared A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC166111/
https://ncbi.nlm.nih.gov/pubmed/12878541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2682-2684.2003
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