Correlation of Daptomycin Bactericidal Activity and Membrane Depolarization in Staphylococcus aureus

The objective of this study was to further elucidate the role of membrane potential in the mechanism of action of daptomycin, a novel lipopeptide antibiotic. Membrane depolarization was measured by both fluorimetric and flow cytometric assays. Adding daptomycin (5 μg/ml) to Staphylococcus aureus gra...

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Bibliografiske detaljer
Main Authors: Silverman, Jared A., Perlmutter, Nancy G., Shapiro, Howard M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166110/
https://ncbi.nlm.nih.gov/pubmed/12878516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2538-2544.2003
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