Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus

The ability of daptomycin to produce bactericidal activity against Staphylococcus aureus while causing negligible cell lysis has been demonstrated using electron microscopy and the membrane integrity probes calcein and ToPro3. The formation of aberrant septa on the cell wall, suggestive of impairmen...

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Bibliografiske detaljer
Main Authors: Cotroneo, Nicole, Harris, Robert, Perlmutter, Nancy, Beveridge, Terry, Silverman, Jared A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415783/
https://ncbi.nlm.nih.gov/pubmed/18378708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01410-07
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