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Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney

Diabetes mellitus is the most common and rapidly growing cause of end-stage renal disease in developed countries. A classic hallmark of early diabetes mellitus includes activation of the renin-angiotensin system (RAS), which may lead to hypertension and renal tissue injury, but the mechanism of RAS...

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Hlavní autoři: Toma, Ildikó, Kang, Jung Julie, Sipos, Arnold, Vargas, Sarah, Bansal, Eric, Hanner, Fiona, Meer, Elliott, Peti-Peterdi, János
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413183/
https://ncbi.nlm.nih.gov/pubmed/18535668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33293
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