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Connexin 30 Deficiency Impairs Renal Tubular ATP Release and Pressure Natriuresis
In the renal tubule, ATP is an important regulator of salt and water reabsorption, but the mechanism of ATP release is unknown. Several connexin (Cx) isoforms form mechanosensitive, ATP-permeable hemichannels. We localized Cx30 to the nonjunctional apical membrane of cells in the distal nephron and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723976/ https://ncbi.nlm.nih.gov/pubmed/19478095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008101099 |
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