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ATP Releasing Connexin 30 Hemichannels Mediate Flow-Induced Calcium Signaling in the Collecting Duct

ATP in the renal tubular fluid is an important regulator of salt and water reabsorption via purinergic calcium signaling that involves the P2Y(2) receptor, ENaC, and AQP2. Recently, we have shown that connexin (Cx) 30 hemichannels are localized to the non-junctional apical membrane of cells in the d...

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Bibliographic Details
Main Authors: Svenningsen, Per, Burford, James L., Peti-Peterdi, János
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797415/
https://ncbi.nlm.nih.gov/pubmed/24137132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00292
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