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Connexin 30 Deficiency Impairs Renal Tubular ATP Release and Pressure Natriuresis

In the renal tubule, ATP is an important regulator of salt and water reabsorption, but the mechanism of ATP release is unknown. Several connexin (Cx) isoforms form mechanosensitive, ATP-permeable hemichannels. We localized Cx30 to the nonjunctional apical membrane of cells in the distal nephron and...

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Bibliografske podrobnosti
Main Authors: Sipos, Arnold, Vargas, Sarah L., Toma, Ildikó, Hanner, Fiona, Willecke, Klaus, Peti-Peterdi, János
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723976/
https://ncbi.nlm.nih.gov/pubmed/19478095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008101099
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