Activation of the Succinate Receptor GPR91 in Macula Densa Cells Causes Renin Release

Macula densa (MD) cells of the juxtaglomerular apparatus (JGA) are salt sensors and generate paracrine signals that control renal blood flow, glomerular filtration, and release of the prohypertensive hormone renin. We hypothesized that the recently identified succinate receptor GPR91 is present in M...

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Bibliographic Details
Main Authors: Vargas, Sarah Laurin, Toma, Ildikó, Kang, Jung Julie, Meer, Elliott James, Peti-Peterdi, János
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2009
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678039/
https://ncbi.nlm.nih.gov/pubmed/19389848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008070740
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