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Activation of the Succinate Receptor GPR91 in Macula Densa Cells Causes Renin Release

Macula densa (MD) cells of the juxtaglomerular apparatus (JGA) are salt sensors and generate paracrine signals that control renal blood flow, glomerular filtration, and release of the prohypertensive hormone renin. We hypothesized that the recently identified succinate receptor GPR91 is present in M...

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Detalhes bibliográficos
Main Authors: Vargas, Sarah Laurin, Toma, Ildikó, Kang, Jung Julie, Meer, Elliott James, Peti-Peterdi, János
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678039/
https://ncbi.nlm.nih.gov/pubmed/19389848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008070740
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