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Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney
Diabetes mellitus is the most common and rapidly growing cause of end-stage renal disease in developed countries. A classic hallmark of early diabetes mellitus includes activation of the renin-angiotensin system (RAS), which may lead to hypertension and renal tissue injury, but the mechanism of RAS...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413183/ https://ncbi.nlm.nih.gov/pubmed/18535668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33293 |
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