Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.

Previous transgenic work demonstrated transforming activity of the human T-cell leukemia virus type I Tax protein in fibroblasts. In the present study, a Thy-1-based vector was used to express Tax in thymocytes. These mice developed no functional or neoplastic abnormalities of T cells but developed...

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Bibliografske podrobnosti
Main Authors: Nerenberg, M I, Minor, T, Price, J, Ernst, D N, Shinohara, T, Schwarz, H
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC240995/
https://ncbi.nlm.nih.gov/pubmed/2033674
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