Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.

Previous transgenic work demonstrated transforming activity of the human T-cell leukemia virus type I Tax protein in fibroblasts. In the present study, a Thy-1-based vector was used to express Tax in thymocytes. These mice developed no functional or neoplastic abnormalities of T cells but developed...

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Udgivet i:J Virol
Main Authors: Nerenberg, M I, Minor, T, Price, J, Ernst, D N, Shinohara, T, Schwarz, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2033674/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.6.3349-3353.1991
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