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Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.
Previous transgenic work demonstrated transforming activity of the human T-cell leukemia virus type I Tax protein in fibroblasts. In the present study, a Thy-1-based vector was used to express Tax in thymocytes. These mice developed no functional or neoplastic abnormalities of T cells but developed...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1991
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2033674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.6.3349-3353.1991 |
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