Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors

Local adenoviral gene transfer can be performed by means of isolated hepatic perfusion (IHP). This methodology is a very effective and safe way to deliver adenoviral vectors. We studied the immune response after IHP. A decreased neutralising antibody formation was observed, offering possibilities fo...

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Detalhes bibliográficos
Main Authors: van Etten, B, Eggermont, A M M, Ambagtsheer, G, van Tiel, S T, ten Hagen, T L M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409916/
https://ncbi.nlm.nih.gov/pubmed/15480435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602151
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