Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion

Several possible mechanisms for the synergistic anti-tumour effects between tumour necrosis factor alpha (TNF-α) and melphalan after isolated limb perfusion (ILP) have been presented. We found a significant sixfold increase in melphalan tumour tissue concentration after ILP when TNF-α was added to t...

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Detalhes bibliográficos
Main Authors: de Wilt, J H W, ten Hagen, T L M, de Boeck, G, van Tiel, S T, de Bruijn, E A, Eggermont, A M M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374420/
https://ncbi.nlm.nih.gov/pubmed/10737379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1032
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