TNF- α augments intratumoural concentrations of doxorubicin in TNF- α -based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects

We have shown previously that isolated limb perfusion (ILP) in sarcoma-bearing rats results in high response rates when melphalan is used in combination with tumour necrosis factor alpha (TNF-α). This is in line with observations in patients. Here we show that ILP with doxorubicin in combination wit...

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Detalhes bibliográficos
Main Authors: van der Veen, A H, de Wilt, J H W, Eggermont, A M M, van Tiel, S T, Seynhaeve, A L B, ten Hagen, T L M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374400/
https://ncbi.nlm.nih.gov/pubmed/10732774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1027
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