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Lack of efficacy of Doxil® in TNF-α-based isolated limb perfusion in sarcoma-bearing rats
Here we show that Doxil® has minimal antitumour activity in the isolated limb perfusion (ILP) setting and its activity was not enhanced by the addition of tumour necrosis factor (TNF). Doxil® accumulation in tumour tissue was low and also not augmented by TNF. In contrast, activity of free conventio...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409755/ https://ncbi.nlm.nih.gov/pubmed/15208623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601688 |
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