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Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors
Local adenoviral gene transfer can be performed by means of isolated hepatic perfusion (IHP). This methodology is a very effective and safe way to deliver adenoviral vectors. We studied the immune response after IHP. A decreased neutralising antibody formation was observed, offering possibilities fo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409916/ https://ncbi.nlm.nih.gov/pubmed/15480435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602151 |
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