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Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells
Reduced accumulation of cisplatin is the most consistent feature seen in cisplatin-resistant (CP-r) cells that are cross-resistant to other cytotoxic compounds, such as methotrexate. In this report, defective uptake of a broad range of compounds, including [(14)C]-carboplatin, [(3)H]MTX, [(3)H]folic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409801/ https://ncbi.nlm.nih.gov/pubmed/15199393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601956 |
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