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The small GTPase Rac1 is required for smooth muscle contraction

The role of the small GTP-binding protein Rac1 in smooth muscle contraction was examined using small molecule inhibitors (EHT1864, NSC23766) and a novel smooth muscle-specific, conditional, Rac1 knockout mouse strain. EHT1864, which affects nucleotide binding and inhibits Rac1 activity, concentratio...

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Autori principali: Rahman, Awahan, Davis, Benjamin, Lövdahl, Cecilia, Hanumaiah, Veena T, Feil, Robert, Brakebusch, Cord, Arner, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948555/
https://ncbi.nlm.nih.gov/pubmed/24297853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.262998
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