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The Rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain

Progenitor cells in the ventricular zone (VZ) and subventricular zone (SVZ) of the developing forebrain give rise to neurons and glial cells, and are characterized by distinct morphologies and proliferative behaviors. The mechanisms that distinguish VZ and SVZ progenitors are not well understood, al...

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Main Authors: Leone, Dino P., Srinivasan, Karpagam, Brakebusch, Cord, McConnell, Susan K.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929936/
https://ncbi.nlm.nih.gov/pubmed/20506362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20804
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