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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells

The platinum compound oxaliplatin has been shown to be an effective chemotherapeutic agent for the treatment of colorectal cancer. In this study, we investigate the molecular mechanisms of action of oxaliplatin to identify means of predicting response to this agent. Exposure of colon cancer cells to...

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Autors principals: Arango, D, Wilson, A J, Shi, Q, Corner, G A, Arañes, M J, Nicholas, C, Lesser, M, Mariadason, J M, Augenlicht, L H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409767/
https://ncbi.nlm.nih.gov/pubmed/15545975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602215
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