Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells

The platinum compound oxaliplatin has been shown to be an effective chemotherapeutic agent for the treatment of colorectal cancer. In this study, we investigate the molecular mechanisms of action of oxaliplatin to identify means of predicting response to this agent. Exposure of colon cancer cells to...

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Bibliografiske detaljer
Main Authors: Arango, D, Wilson, A J, Shi, Q, Corner, G A, Arañes, M J, Nicholas, C, Lesser, M, Mariadason, J M, Augenlicht, L H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Molecular and Cellular Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409767/
https://ncbi.nlm.nih.gov/pubmed/15545975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602215
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