Oxaliplatin/capecitabine vs oxaliplatin/infusional 5-FU in advanced colorectal cancer: the MRC COIN trial

BACKGROUND: COIN compared first-line continuous chemotherapy with the same chemotherapy given intermittently or with cetuximab in advanced colorectal cancer (aCRC). METHODS: Choice between oxaliplatin/capecitabine (OxCap) and oxaliplatin/leucovorin (LV)/infusional 5-FU (OxFU) was by physician and pa...

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Detalhes bibliográficos
Main Authors: Madi, A, Fisher, D, Wilson, R H, Adams, R A, Meade, A M, Kenny, S L, Nichols, L L, Seymour, M T, Wasan, H, Kaplan, R, Maughan, T S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461171/
https://ncbi.nlm.nih.gov/pubmed/22935584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.384
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