Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience

We present the preliminary toxicity data from the MRC COIN trial, a phase III randomised controlled trial of first-line therapy in advanced colorectal cancer, with particular reference to the addition of cetuximab to an oxaliplatin–fluoropyrimidine combination. A total of 804 patients were randomise...

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Detalhes bibliográficos
Main Authors: Adams, R A, Meade, A M, Madi, A, Fisher, D, Kay, E, Kenny, S, Kaplan, R S, Maughan, T S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634710/
https://ncbi.nlm.nih.gov/pubmed/19165196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604877
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