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CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer

It has recently become clear that CDH13 (H-cadherin, T-cadherin) expression is frequently silenced by aberrant methylation in colorectal cancers and adenomas. In this study, we investigated the methylation status of CDH13 gene and detected aberrant promoter methylation in 27 of 84 (32%) colorectal c...

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Detalhes bibliográficos
Main Authors: Hibi, K, Nakayama, H, Kodera, Y, Ito, K, Akiyama, S, Nakao, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409627/
https://ncbi.nlm.nih.gov/pubmed/14997203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601647
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