CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer

It has recently become clear that CDH13 (H-cadherin, T-cadherin) expression is frequently silenced by aberrant methylation in colorectal cancers and adenomas. In this study, we investigated the methylation status of CDH13 gene and detected aberrant promoter methylation in 27 of 84 (32%) colorectal c...

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Bibliografiske detaljer
Main Authors: Hibi, K, Nakayama, H, Kodera, Y, Ito, K, Akiyama, S, Nakao, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Molecular and Cellular Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409627/
https://ncbi.nlm.nih.gov/pubmed/14997203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601647
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