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c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
The proto-oncogene c-Myc is overexpressed in 70% of colorectal tumours and can modulate proliferation and apoptosis after cytotoxic insult. Using an isogenic cell system, we demonstrate that c-Myc overexpression in colon carcinoma LoVo cells resulted in sensitisation to camptothecin-induced apoptosi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394410/ https://ncbi.nlm.nih.gov/pubmed/14583781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601338 |
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