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α-Tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-κB activation

Activation of nuclear factor-κB (NF-κB) can interfere with induction of apoptosis triggered by the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL; Apo2L). Therefore, agents that suppress NF-κB activation may sensitise cells to TRAIL-dependent apoptosis. Exposure of Jurkat cells to T...

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Detalhes bibliográficos
Main Authors: Dalen, H, Neuzil, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376774/
https://ncbi.nlm.nih.gov/pubmed/12556975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600683
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