α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human malignant mesothelioma cells

Malignant mesothelioma (MM) is a fatal type of neoplasia with poor therapeutic prognosis, largely due to resistance to apoptosis. We investigated the apoptotic effect of α-tocopheryl succinate (α-TOS), a strong proapoptotic agent, in combination with the immunological apoptogen TNF-related apoptosis...

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Bibliografiske detaljer
Main Authors: Tomasetti, M, Rippo, M R, Alleva, R, Moretti, S, Andera, L, Neuzil, J, Procopio, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409711/
https://ncbi.nlm.nih.gov/pubmed/15083198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601707
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