The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma

Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate and homocysteine metabolism important for DNA integrity in 31 PCNSL patients and 142 controls. We found significantly less carriers of the me...

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Bibliografische gegevens
Hoofdauteurs: Linnebank, M, Schmidt, S, Kolsch, H, Linnebank, A, Heun, R, Schmidt-Wolf, I G H, Glasmacher, A, Fliessbach, K, Klockgether, T, Schlegel, U, Pels, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2004
Onderwerpen:
Genetics and Genomics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409477/
https://ncbi.nlm.nih.gov/pubmed/15138479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601777
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