Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma

BACKGROUND: Chemotherapy for primary central nervous system lymphoma (PCNSL) is based on methotrexate (MTX), which interferes with both nucleic acid synthesis and methionine metabolism. We have reported previously that genetic variants with influence on methionine metabolism are associated with MTX...

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Detalhes bibliográficos
Main Authors: Linnebank, M, Moskau, S, Kowoll, A, Semmler, A, Bangard, C, Vogt-Schaden, M, Egerer, G, Schackert, G, Reichmann, H, Schmidt-Wolf, I G H, Pels, H, Schlegel, U
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504945/
https://ncbi.nlm.nih.gov/pubmed/23099805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.476
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