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Transcobalamin C776G Genotype Modifies the Association between Vitamin B12 and Homocysteine in Older Hispanics

BACKGROUND: A common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259. This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues. METHODS: TC genotype and its associations with in...

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Autors principals: Garrod, Marjorie G., Allen, Lindsay H., Haan, Mary N., Green, Ralph, Miller, Joshua W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864787/
https://ncbi.nlm.nih.gov/pubmed/20216556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejcn.2010.20
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