The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma

Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate and homocysteine metabolism important for DNA integrity in 31 PCNSL patients and 142 controls. We found significantly less carriers of the me...

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Detalhes bibliográficos
Main Authors: Linnebank, M, Schmidt, S, Kolsch, H, Linnebank, A, Heun, R, Schmidt-Wolf, I G H, Glasmacher, A, Fliessbach, K, Klockgether, T, Schlegel, U, Pels, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409477/
https://ncbi.nlm.nih.gov/pubmed/15138479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601777
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