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Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas
BACKGROUND: We have used a mouse model based on overexpression of c-Myc in B cells genetically engineered to be self-reactive to test the hypothesis that farnesyl transferase inhibitors (FTIs) can effectively treat mature B cell lymphomas. FTIs are undergoing clinical trials to treat both lymphoid a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409375/ https://ncbi.nlm.nih.gov/pubmed/18489761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-39 |
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