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Working together: Farnesyl transferase inhibitors and statins block protein prenylation

Farnesyl transferase inhibitors (FTIs) have so far proved to have limited value as single agents in clinical trials. This PharmSight will focus on the use of a novel group of FTIs that are most effective in vitro when used in combination with the “statin” class of anti-hypercholesterolemic agents, w...

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Bibliographic Details
Main Authors: Wojtkowiak, Jonathan W., Gibbs, Richard A., Mattingly, Raymond R.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858423/
https://ncbi.nlm.nih.gov/pubmed/20419048
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