Wird geladen...

Prion detection by an amyloid seeding assay

Polymerization of recombinant prion protein (recPrP), which was produced in bacteria, into amyloid fibers was accompanied by the acquisition of prion infectivity. We report here that partially purified preparations of prions seed the polymerization of recPrP into amyloid as detected by a fluorescenc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Colby, David W., Zhang, Qiang, Wang, Shuyi, Groth, Darlene, Legname, Giuseppe, Riesner, Detlev, Prusiner, Stanley B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409241/
https://ncbi.nlm.nih.gov/pubmed/18096717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710152105
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!