Chromosomal Instability by Inefficient Mps1 Auto-Activation Due to a Weakened Mitotic Checkpoint and Lagging Chromosomes

BACKGROUND: Chromosomal instability (CIN), a feature widely shared by cells from solid tumors, is caused by occasional chromosome missegregations during cell division. Two of the causes of CIN are weakened mitotic checkpoint signaling and persistent merotelic attachments that result in lagging chrom...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jelluma, Nannette, Brenkman, Arjan B., McLeod, Ian, Yates, John R., Cleveland, Don W., Medema, René H., Kops, Geert J. P. L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408436/
https://ncbi.nlm.nih.gov/pubmed/18545697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002415
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares