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Targeting the Mitotic Checkpoint to Kill Tumor Cells

One of the most common hallmarks of cancer cells is aneuploidy or an abnormal number of chromosomes. This abnormal chromosome content is a consequence of chromosome missegregation during mitosis, a defect that is seen more frequently in tumor cell divisions as in normal cell divisions. In fact, a la...

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Bibliografische gegevens
Hoofdauteurs: Janssen, Aniek, Kops, Geert J., Medema, René H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer-Verlag 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056011/
https://ncbi.nlm.nih.gov/pubmed/21475725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-010-0059-x
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