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Targeting the Mitotic Checkpoint to Kill Tumor Cells
One of the most common hallmarks of cancer cells is aneuploidy or an abnormal number of chromosomes. This abnormal chromosome content is a consequence of chromosome missegregation during mitosis, a defect that is seen more frequently in tumor cell divisions as in normal cell divisions. In fact, a la...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056011/ https://ncbi.nlm.nih.gov/pubmed/21475725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-010-0059-x |
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