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Metabolism of 17α-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons
Recent data from our laboratory revealed the formation of an unknown metabolite of 17 hydroxyprogestrone caproate (17-HPC), used for treatment of preterm deliveries, during its perfusion across the dually perfused human placental lobule. Previously, we demonstrated that the drug is not hydrolyzed, n...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2408387/ https://ncbi.nlm.nih.gov/pubmed/18329004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.01.013 |
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