RNA sequence variants in live poliovirus vaccine and their relation to neurovirulence.

Mutant analysis by polymerase chain reaction and restriction enzyme cleavage (MAPREC) was used to study sequence heterogeneity and stability in attenuated poliovirus type 3 at positions in which the vaccine virus differs from its wild-type progenitor. Of seven genomic positions tested, only two (pos...

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Detaylı Bibliyografya
Yayımlandı:	J Virol
Asıl Yazarlar:	Chumakov, K M, Norwood, L P, Parker, M L, Dragunsky, E M, Ran, Y X, Levenbook, I S
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1992
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1309923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.2.966-970.1992
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RNA sequence variants in live poliovirus vaccine and their relation to neurovirulence.

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