Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis

Insulin-like growth factor-binding protein-3 (IGFBP-3) regulates IGF bioactivity and also independently modulates cell growth and survival. By using a yeast two-hybrid screen to identify IGFBP-3-interacting proteins, we cloned humanin (HN) as an IGFBP-3-binding partner. HN is a 24-aa peptide that ha...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ikonen, Maaria, Liu, Bingrong, Hashimoto, Yuichi, Ma, Liqun, Lee, Kuk-Wha, Niikura, Takako, Nishimoto, Ikuo, Cohen, Pinchas
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14561895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2135111100
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires