Insulin-Like Growth Factor I (IGF-I) Protects Cells from Apoptosis by Alzheimer's V642I Mutant Amyloid Precursor Protein through IGF-I Receptor in an IGF-Binding Protein-Sensitive Manner

It has been found that insulin-like growth factor I (IGF-I) exerts cytoprotection against Aβ amyloid-induced neuronal cell death. Deposits of Aβ amyloid are one of the pathological hallmarks of Alzheimer's disease (AD). Here, we examined whether IGF-I exerts protective activity against cell dea...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Niikura, Takako, Hashimoto, Yuichi, Okamoto, Takashi, Abe, Yoichiro, Yasukawa, Takashi, Kawasumi, Masaoki, Hiraki, Takako, Kita, Yoshiko, Terashita, Kenzo, Kouyama, Keisuke, Nishimoto, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762606/
https://ncbi.nlm.nih.gov/pubmed/11245675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-06-01902.2001
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