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mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

The mechanisms that regulate mammalian cell size during development and homeostatic maintenance are poorly understood. The tumor suppressor Pten is required for correct maintenance of mammalian neuronal soma size. Selective inactivation of Pten in postnatal granule neurons of the cerebellum and dent...

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Bibliografische gegevens
Hoofdauteurs: Kwon, Chang-Hyuk, Zhu, Xiaoyan, Zhang, Junyuan, Baker, Suzanne J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC240720/
https://ncbi.nlm.nih.gov/pubmed/14534328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2132711100
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