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Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli

The crystal structure of the Escherichia coli lactose permease at 3.5 Å with a bound substrate has been reported recently. The structure reveals the sugar–protein contacts, which include hydrophobic stacking between the galactopyranosyl ring of substrate and the indole side chain of Trp-151, as prop...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Vázquez-Ibar, José Luis, Guan, Lan, Svrakic, Maja, Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14566061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1835645100
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