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Unraveling the mechanism of the lactose permease of Escherichia coli

We studied the effect of pH on ligand binding in wild-type lactose permease or mutants in the four residues—Glu-269, Arg-302, His-322, and Glu-325—that are the key participants in H(+) translocation and coupling between sugar and H(+) translocation. Although wild-type permease or mutants in Glu-325...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sahin-Tóth, Miklós, Karlin, Arthur, Kaback, H. Ronald
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27091/
https://ncbi.nlm.nih.gov/pubmed/10984523
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